Publications

In press

Validation of the Oncomine focus panel for NGS for clinical tumour samples. Williams H, Walsh K, Diamond, A, Oniscu A, Deans Z. Virchow Arch In press.

Published

Best Practice for integrating cell-free DNA based NIPT into clinical practice. Zandra C. Deans, Nicola Wolstenholme, Ros J Hastings. Non-invasive Prenatal Testing (NIPT), Chapter 12. Elsevier Press. 

Results of the UK NEQAS for Molecular Genetics Reference Sample analysis. Richman SD, Fairley J, Hall JA, Nataraj N, Bhide M, Lau A, Norman KL, Deans ZC. J Clin Pathol. 2018 Jul 20. pii: jclinpath-2018-205277. 

International pilot external quality assessment scheme for analysis and reporting of circulating tumour DNA. Keppens C, Dequeker EMC, Patton SJ, Normanno N, Fenizia F, Butler R, Cheetham M, Fairley JA, Williams H, Hall JA, Schuuring E, Deans ZC. BMC Cancer. 2018 Aug 9;18(1):804.

European Cytogeneticist Association (ECA) newsletter (41) Jan 2018

Delivering an accredited non-invasive prenatal diagnosis service for monogenic disorders and recommendations for best practice. Jenkins LA, Deans ZC, Lewis C, Allen S. Prenat Diagn. 2018,38:44-51

European Guidelines for Constitutional Cytogenomic Analysis.  (2018) Silva M, Leeuw N, Mann K, Schuring-Blom H, Morgan M, Giardino D, Rack K,  Hastings. R. Eur J Hum Genet.

Recommended practice for laboratory reporting of non-invasive prenatal testing of trisomies 13, 18 and 21: a consensus opinionDeans ZC, Allen S, Jenkins L, Khawaja F, Hastings RJ, Mann K, Patton SJ, Sistermans EA, Chitty LS. Prenat Diagn. 2017 Jul;37(7):699-704. doi: 10.1002/pd.5068. Epub 2017 Jun 8.

How close are we to standardised extended RAS gene mutation testing? The UK NEQAS evaluation. Richman SD et al. J Clin Pathol. 2017 Jan;70(1):58-62.

Integration of next-generation sequencing in clinical diagnostic molecular pathology laboratories for analysis of solid tumours; an expert opinion on behalf of IQN Path ASBL. Deans ZC et al. Virchows Arch. 2017 Jan;470(1):5-20.             

The ins and outs of molecular pathology reporting. Tack V, Dufraing K, Deans ZC, van Krieken HJ, Dequeker EM. Virchows Arch. 2017 Mar 26.

Developing effective ctDNA testing services for lung cancer PHG Foundation Report (2017). Laura Blackburn, Leila Luheshi, Sandi Deans, Mark Kroese and Hilary Burton.

Review of the implementation of plasma ctDNA testing on behalf of IQN Path ASBL: A perspective from an EQA providers survey. Zandra C Deans, Hannah Williams, Elisabeth MC Dequeker, Cleo Keppens, Nicola Normanno, Ed Shuuring, Simon Patton, Melanie Cheetham, Rachel Butler, Jacqueline Hall. Virchows Archiv. 2017 Aug 25.

RAS screening in colorectal cancer: A comprehensive analysis of the results from the UK NEQAS Colorectal Cancer External Quality Assurance schemes (2009-2016). Susan D. Richman, Jennifer Fairley, Rachel Butler, Zandra C. Deans. Virchows Archiv. 2017 Jun 26.

Delivering an accredited non-invasive prenatal diagnosis service for monogenic disorders and recommendations for best practice. Jenkins LA, Deans ZC, Lewis C, Allen S.Prenat Diagn. 2017 Dec 20. doi: 10.1002/pd.5197. [Epub ahead of print]

Cytogenetic nomenclature and reporting. Stevens-Kroef M, Simons A, Rack K, Hastings RJ. Methods Mol Biol. 2017;1541:303-309. Review

Fading competence of cytogenetic diagnostic laboratories: the alarm bell has started to ring. Hochstenbach R, Slunga-Tallberg A, Devlin C, Floridia G, de Alba MR, Bhola S, Rack K, Hastings R. Eur J Hum Genet. 2017 Feb;25(3):273-274.

HGVS Nomenclature in Practice: An Example from the United Kingdom National External Quality Assessment Scheme. Deans ZC, Fairley JA, den Dunnen JT, Clark C. Hum Mutat. Jun;37(6):576-8. doi: 10.1002/humu.22978. Epub 2016 Mar 18

What's in a Name? A Coordinated Approach toward the Correct Use of a Uniform Nomenclature to Improve Patient Reports and Databases. Tack V, Deans ZC, Wolstenholme N, Patton S, Dequeker EM. Hum Mutat. 2016 Jun;37(6):570-5. doi: 10.1002/humu.22975. Epub 2016 Mar 14 

Raising the standards of routine genetic testing. Zandra Deans Hospital Healthcare Europe 2015. 

Guidance for laboratories performing molecular pathology for cancer patients. Cree IA, Deans Z, Ligtenberg MJ, Normanno N, Edsjö A, Rouleau E, Solé F, Thunnissen E, Timens W, Schuuring E, Dequeker E, Murray S, Dietel M, Groenen P, Van Krieken JH; European Society of Pathology Task Force on Quality Assurance in Molecular Pathology and the Royal College of Pathologists. J Clin Pathol. 2014 Nov;67(11):923-31

Next generation diagnostic molecular pathology: critical appraisal of quality assurance in Europe. Dubbink HJ, Deans ZC, Tops BB, van Kemenade FJ, Koljenović S, van Krieken HJ, Blokx WA, Dinjens WN, Groenen PJ. Mol Oncol. 2014 Jun;8(4):830-9. doi: 10.1016/j.molonc.2014.03.004. Epub 2014 Mar 18. Epub 2014 Jul 10.

External quality assessment of BRAF molecular analysis in melanoma. Deans ZC, Wallace A, O'Sullivan B, Purvis A, Camus S, Fairley JA, Gonzalez D. J Clin Pathol. 2014 Feb;67(2):120-4. doi: 10.1136/jclinpath-2013-201848. Epub 2013 Oct 4.

European consensus conference for external quality assessment in molecular pathology. van Krieken JH, Siebers AG,Normanno N, Blackhall F, Boone E, Hartziekenhuis H, Botti G, Carneiro F, Celik I, Ciardiello F, Cree IA, Deans ZC,Dequeker E, Edsjö A, Groenen PJ, Kamarainen O, Kreipe HH, van Krieken JH, Ligtenberg MJ, Marchetti A, Murray S,Normanno N, Opdam FJ, Patterson SD, Patton S, Pinto C, Rouleau E, Schuuring E, Siebers AG, Sterck S, Taron M,Tejpar S, Timens W, Thunnissen E, van de Ven PM. Ann Oncol. 2013 Aug;24(8):1958-63. doi: 10.1093/annonc/mdt153. Epub 2013 Apr 23.

Improvement in the quality of molecular analysis of EGFR in non-small cell lung cancer detected by three rounds of external quality assessment. Deans ZC, Bilbe N, O'Sullivan B, Lazarou LP, de Castro DG, Parry S, Dodson A, Taniere P, Clark C, Butler R. J Clin Pathol. 2013 Apr;66(4):319-25. doi: 10.1136/jclinpath-2012-201227. Epub 2013 Feb 1.

The UK NEQAS for Molecular Genetics scheme for gastrointestinal stromal tumour: findings and recommendations following four rounds of circulation. Wong NA, Deans ZC, Ramsden SC. J Clin Pathol. 2012 Sep;65(9):786-90. doi: 10.1136/jclinpath-2012-200851. Epub 2012 Jun 9.

Guideline on the requirements of external quality assessment programs in molecular pathology. van Krieken JH, Normanno N, Blackhall F, Boone E, Botti G, Carneiro F, Celik I, Ciardiello F, Cree IA, Deans ZC, Edsjö A, Groenen PJ, Kamarainen O, Kreipe HH, Ligtenberg MJ, Marchetti A, Murray S, Opdam FJ, Patterson SD, Patton S, Pinto C, Rouleau E, Schuuring E, Sterck S, Taron M, Tejpar S, Timens W, Thunnissen E, van de Ven PM, Siebers AG, Dequeker E. Virchows Arch. 2013 Jan;462(1):27-37. Epub 2012 Dec 19.

The experience of three years of external quality assessment of preimplantation genetic diagnosis for cystic fibrosis. Deans Z, Fiorentino F, Biricik A, Traeger-Synodinos J, Moutou C, De Rycke M, Renwick P, Sengupta S, Goossens V, Harton G. Eur J Hum Genet. 2013 Aug;21(8):800-6. doi: 10.1038/ejhg.2012.244. Epub 2012 Nov 14.

Molecular genetics external quality assessment pilot scheme for KRAS analysis in metastatic colorectal cancer. Deans ZC, Tull J, Beighton G, Abbs S, Robinson DO, Butler R. Genet Test Mol Biomarkers. 2011 Nov;15(11):777-83. doi: 10.1089/gtmb.2010.0239. Epub 2011 Aug 18.

Monitoring standards for molecular genetics testing in the United Kingdom, the Netherlands and Ireland. Ramsden SC,Deans Z, Robinson DO, Mountford R, Sistermans EA, Grody WW, McQuaid S, Patton SJ, Stenhouse SA. Genet Test. 2006 Fall;10(3):147-56.

 

 

Last updated: Wednesday, 05 December 2018
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